IXTAL is a research-driven company that provides solutions in the field of protein science and structural biology.

IXTAL offers discovery services for the production and purification of target proteins, their biochemical and biophysical characterisation.


Cloning, Expression and Purification of Proteins

Cloning strategies

Heterologous expression of proteins

Recombinant protein production

Protein chromatography purification


Protein Analysis

Biochemical and biophysical characterisation

Electrophoretic analysis

Protein-protein and protein-ligand interaction studies


Protein Engineering

Random mutagenesis

Site-directed mutagenesis

Chimeric proteins


Clients and partners

Our network


Desole, C. et al. Engineering, characterization, and biological evaluation of an antibody targeting the HGF receptor Frontiers in Immunology, 2021 View at Publisher

Merlo, R. et al. The SNAP-tag technology revised: an effective chemo-enzymatic approach by using a universal azide-based substrate Frontiers in Immunology, 2021, 36:85-97 View at Publisher

Ferrario, E. et al. Structure of Thermococcus litoralis Δ1-pyrroline-2-carboxylate reductase in complex with NADH and L-proline Acta Crystallographica, 2020, D76:496-505. View at Publisher

Ferraris, D.M. et al. Structure of Thermococcus litoralis trans-3-hydroxy-l-proline dehydratase in the free and substrate-complexed form Biochemical and Biophysical Research Communications, 2019, 516(1):189-195. View at Publisher

Rossi, F. et al. Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe Biochemical and Biophysical Research Communications, 2018, 500(3):698-703. View at Publisher

Sarno, S. et al. Absolute structure and structure-function relationships of 4R,2′R and 4S,2′S Pidotimod® Journal of Molecular Structure, 2017, 1147:810-814. View at Publisher

Get in touch

Main Office
via Bovio 6
28100 Novara (Italy)
Phone: (+39) 0321.375.715
Fax: (+39) 0321.375.821
P.I. 02426370033
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