IXTAL is a research-driven company that provides solutions in the field of protein science, structural biology and drug design.
IXTAL offers discovery services for the production and purification of target proteins, their biochemical and biophysical characterisation, and their X-ray structural analysis.
IXTAL services and expertise include in silico drug design, lead optimisation and small molecule X-ray diffraction for single crystal structure determination.
IXTAL has been invited to present at the “Industrial and Molecular Biotechnologies” session of the 59th Congress of the Italian Society of Biochemistry and Molecular Biology (SIB), that will take place from the 20th to 22nd of September 2017 in Caserta (Italy). For more info: www.sib2017.it
Heterologous expression of proteins
Recombinant protein production
Protein chromatography purification
Biochemical and biophysical characterisation
Protein-protein and protein-ligand interaction studies
Robot-assisted crystallization screening
X-ray data collection and analysis
Molecular docking simulation
Molecular dynamics simulation
Rossi, F. et al. Crystal structure of a thermophilic O6-alkylguanine-DNA alkyltransferase-derived self-labeling protein-tag in covalent complex with a fluorescent probe Biochemical and Biophysical Research Communications. Just accepted.
Sarno, S. et al. Absolute structure and structure-function relationships of 4R,2′R and 4S,2′S Pidotimod® Journal of Molecular Structure. Volume 1147, 5 November 2017, Pages 810-814. View at Publisher